Jaguars vs. Titans prediction: Trevor Lawrence, Jacksonville pull out tough win against pesky Tennessee
The Jaguars strengthen their position in the AFC playoff picture with a victory
Bills vs. Steelers prediction: Pittsburgh will upset Buffalo in Aaron Rodgers' return start
Which AFC playoff contender will get back on track?
Texans vs. Colts prediction: C.J. Stroud wins in return as Houston's defense stops Daniel Jones, Indianapolis
There are questions about how both quarterbacks will perform amid recent setbacks
Rams vs. Panthers prediction: Los Angeles will maintain its standing atop NFC, but Carolina won't go quietly
The Rams can win their seventh straight game and Matthew Stafford can strengthen his MVP case
49ers vs. Browns prediction: Will Cleveland upset San Francisco in Shedeur Sanders' first home start?
The 'Niners may be favored, but the Browns did pull an upset the last time they met
2025 Black Friday NFL game predictions, odds: Eagles vs. Bears picks from expert on 40-25 run
Chicago vs. Philadelphia picks for the 2025 NFL Black Friday Game from Adam Silverstein, who is 40-25 on Eagles bets
Eagles vs. Bears SGP: Black Friday NFL same-game parlay picks, bets, props by SportsLine AI Model
SportsLine's Machine Learning Model AI reveals its Bears vs. Eagles SGP in the NFL Black Friday Game that returns more than 6-1
Bills' offensive line depleted as tackles Dion Dawkins, Spencer Brown ruled out for matchup vs. Steelers
The trip to Pittsburgh could prove to be a major challenge for Josh Allen and the Bills
