16 vs. 1 upset rankings: Michigan least likely NCAA Tournament No. 1 seed to lose, but here's who is in danger A No. 16 seed has knocked off a No. 1 seed only twice in 160 opportunities, but both instances occurred recently, so don't rule it out Original Source: https://www.cbssports.com/college-basketball/news/16-vs-1-upset-rankings-michigan-least-likely-ncaa-tournament-no-1-seed-to-lose-but-heres-who-is-in-danger/
