March Madness 2025: Which low seeds have the best chances of pulling a huge first-round upset? Five of the last six men's NCAA tournaments have featured at least one top-three seed losing in the opening round. Original Source: https://sports.yahoo.com/college-basketball/article/march-madness-2025-which-low-seeds-have-the-best-chances-of-pulling-a-huge-first-round-upset-234649972.html